Gore wins $1.13 million NIH grant
Award will fund study into evolution of antibiotic-resistance in bacteria
MIT Assistant Professor of Physics Jeff Gore is receiving a four-year, $1,131,603 grant from the National Institutes of Health, National Institute of General Medical Science, to pursue research into cooperation and cheating in the evolution of antibiotic resistance in bacteria.
The research addresses the rise in antibiotic resistance among bacteria to the most widely used class of antibiotic medicines, called beta-lactam antibiotics. Bacteria can develop resistance to antibiotics like penicillin by expressing an enzyme, beta-lactamase, which inactivates the antibiotic.
“We hypothesize that a tightly integrated combination of experiment and modeling will provide novel insight into how the cooperative nature of bacterial growth in beta-lactam antibiotics influences the evolution of antibiotic resistance,” Gore said in his NIH application. “The proposed studies will provide insight into the evolution of antibiotic resistance and cooperative behaviors more generally.”
The Research Project Grant (R01) is the oldest NIH grant program. The first-year allocation of $283,311 for the NIH R01 award begins April 1, 2013. Read more